Methylcinnamic Acid - China

Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.

Description: 5-Methoxycinnamic acid is a photosensitive compound, also known as para-methoxycinnamate or O-methyl-p-coumarate, belongs to the class of organic compounds known as cinnamic acids.

These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid.

4-Methoxycinnamic acid exists as a solid and is considered to be practically insoluble (in water) and relatively neutral.

4-Methoxycinnamic acid has been detected in multiple biofluids, such as urine and blood.

Within the cell, 4-methoxycinnamic acid is primarily located in the membrane (predicted from logP).

Outside of the human body, 4-methoxycinnamic acid can be found in turmeric and wild celery.

This makes 4-methoxycinnamic acid a potential biomarker for the consumption of these food products.

Main Applications: 1 - methyl cinnamic acid is mainly used as an important intermediate in organic synthesis.

2 - p-MCA exerted antihyperglycemic/hypogly cemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients.

3 - methyl cinnamic acid shows various pharmacologic actions such as hepatoprotective and antihyperglycemic activities, it also can stimulate insulin secretion from pancreatic β-cells by increasing Ca2+ influx via the L-type Ca2+ channels, but not through the closure of ATP-sensitive K+ channels.

4.4-Methoxycinnamic acid can strongly inhibit the diphenolase activity of mushroom tyrosinase, with the IC 50 value of 0.42 mM, and the inhibition is reversible.

5 - Inhibitory effects of cinnamic acid and its derivatives on the diphenolase activity of mushroom ( Agaricus bisporus ) tyrosinase.

6 - Natural products modulate Shigella-host-cell interaction.

7 - Photosensitive semiconductor nanocrystals, photosensitive composition comprising semiconductor nanocrystals and method for forming semiconductor nanocrystal pattern using the same

8 - Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion.

9 - Protective effect of p-methoxycinnamic acid, an active phenolic acid against 1, 2-dimethylhydrazine-induc ed colon carcinogenesis: modulating biotransforming bacterial enzymes and xenobiotic metabolizing enzymes.

Company Contact:

• Posted By: Landmark

• Phone: 18171090921

• Address: Hongtu , Wuhan , Hu Bei, China

• Email:

• Website: https://www.landmarkind.com

• Business Description: Wuhan LANDMARK Industrial Co., Ltd. was established in 2012 and is located in the sub-provincial-level central city of six provinces in central China - Wuhan City, Hubei Province.
  
  The company's factory is located in the chemical concentrating area in east of Liyang, Hubei Province.
  
  It covers an area of more than 200 acres and has a sales office in Jiang'an District of Wuhan City with direct subway access and convenient land and water transportation.
  
  Set up a large-scale warehousing in Dongxihu District of Wuhan City, and the freight radiates nationwide.
  
  The company has an independent research and development center, with independent research and development capabilities and rich production experience, advanced production technology, complete testing equipment.
  
  The existing staff of more than 100 people, including postgraduates and undergraduate or more than 40 people, college staff accounted for 85% of the total number of employees.
  
  The company specializes in the research, development, production and sales of cinnamon series flavors and fragrances, fine chemicals, and food additives.
  
  The company's main products are: cinnamic acid, cinnamaldehyde, cinnamon alcohol, methyl cinnamate, ethyl cinnamate, benzaldehyde and so on.
  
  The company has passed ISO9001 quality management system certification, and relying on the concept of independent development and joint development of universities, it has in-depth cooperation with major universities and scientific research institutions in Wuhan.
  
  It has successively obtained excellent companies with integrity standards, top ten outstanding private enterprises, and corporate credit evaluation AAA.
  
  Grade credit companies, etc.