Raws 3 Bromocinnamic Acid - China

Synonyms：RARECHEM BK HC T307; TRANS-3-BROMOCINNAMIC ACID; M-BROMOCINNAMIC ACID; M-BROMOPHENYLACRYLIC ACID;BROMOCINNAMIC ACID, 3-;3-BROMOCINNAMIC ACID; AKOS BBS-00006566; AKOS B004044

CAS NO.

：32862-97-8

Formula：C9H7BrO2 Molecular weight: 227.05

EINECS NO: 251-267-7

Melting point: 177-179 °C

Appearance: Colorless crystal

Vapor pressure: 0.0±0.8 mmHg at 25°C

Refractive index: 1.648

Storage: Shading, confined preservation, dry, ensure good ventilation or exhaust in the workshop

Stability: Stable under normal temperature and pressure

Key words: 3-Bromocinnamic acid, spices, essence, Synthetic essence, General description

3-Bromocinnamic acid is the metabolite of cinromide (3-bromo-N-ethylcinnamami de) and can be analysed in plasma by high-performance liquid chromatographic method.

Simultaneous determination of the anticonvulsants, cinromide (3-bromo-n-ethylcinnamami de), 3-bromocinnamamide, and carbamazepine in plasma by high-performance liquid chromatography.

3-Bromocinnamic acid is used as organic synthesis of raw materials, fine chemicals, pharmaceutical intermediates.

Abstract

A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamami de) and its de-ethylated metabolite.

Carbamazepine levels can be easily measured by the same technique.

The N-isopropyl analogue of cinromide is used as internal standard, and all compounds are easily separated on a reversed-phase column operated at 55 degrees with a small-diameter pre-column maintained at the same temperature.

The extraction is rapid and generally applicable to plasma and urine samples that are to be analyzed by reversed-phase chromatography.

Short- and long-term reproducibility studies show less than 4% relative standard deviation for replicate determinations for all drugs.

Limits of quantitation are 10-20 ng/ml with an internal standard concentration of 3 micrograms/ml.

Another metabolite of cinromide, 3-bromocinnamic acid, which may have some anticonvulsant effect, can be analyzed simultaneously by buffering the mobile phase and adding an ion-pairing reagent.

Storage: Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.

Specifications

Item REQUIREMENT RESULT

Assay ≥99% 99.20 %

Description Colorless crystal White or slightlyyellow crystal

Melting point 177-179 °C 178°C

Rotation ratio 1.6317-1.6482 1.6471

Company Contact:

• Posted By: Wuhan LANDMARK Industrial Co., Ltd.

• Phone: +8618171091217

• Address: Jiang'an District of Wuhan, Wuhan , China

• Email:

• Website: https://www.landmarkind.com

• Business Description: Landmarkind is a manufacturer of organic from China, low price with best quality for worldwide, have been over 10 years in this market, welcome to email us for inquiry.
  
  Our Products:
  
  - raws 3 phenylacrylonitrile
  
  - raws cinnamoyl chloride
  
  - raws alpha methylcinnamaldehyde
  
  - raws p hydroxycinnamic acid
  
  - raws 3 chlorocinnamic acid
  
  - raws 3 trifluoromethyl cinnamic acid
  
  - raws 3 bromocinnamic acid
  
  - raws 2 fluorocinnamic acid
  
  - raws 2 methylcinnamic acid
  
  - raws 2 methoxycinnamic acid
  
  - raws 2 chlorocinnamic acid
  
  - raws o trifluoromethylcinnamic acid
  
  - raws 2 bromocinnamic acid
  
  - raws hydrogenated cinnamic acid
  
  - raws phenethyl cinnamate
  
  - raws benzyl cinnamate
  
  - raws butyl cinnamate
  
  - raws potassium cinnamate
  
  - raws sodium cinnamate
  
  - raws isopropyl cinnamate 98
  
  - raws isobutyl cinnamate
  
  - raws propyl cinnamate
  
  - raws cinnamamide
  
  - raws eta bromostyrene mixture of cis trans isomers bromo sulphate
  
  - raws cinnamyl acetate