High Quality Alpha Methylcinnamaldehyde - China

Use:

Alpha-methyl cinnamaldehyde is a versatile fragrance commonly used in the fragrance of cosmetics, soaps, foods, etc.

The Alpha-methyl streptopropane obtained by the further reaction thereof is used as a synthetic essence and also has a very good aroma.

At the same time, α-methylcinnamaldehyde is also an important intermediate for the synthesis of the therapeutic drug epalrestat.

As the number of diabetic patients increases, the demand for the drug increases, and the demand for intermediates also increases, and there is an urgent need to improve the process to improve quality.

Production

The chemical name of alpha-methylcinnamic acid is alpha-methylphenylacrolei n, which is an important fine chemical intermediate and is widely used in the production of pharmaceuticals, spices and other products.

At present, there are several methods for preparing alpha-methylcinnamaldehyd e.

1 - Benzoaldehyde and n-propanal are used as raw materials, KF/A1203 is used as a catalyst, and polyethylene glycol is a phase transfer solution to synthesize ct-methyl cinnamaldehyde.

The yield is 78.9 - %.

The yield of alpha-methylcinnamaldehyd e synthesized by the method is high, and the process is relatively simple, but the preparation of the catalyst used is complicated, expensive, and has a little pollution to the environment, and the recycling process is cumbersome.

2, using benzaldehyde and n-propionaldehyde as raw materials, ethanol as solvent, PEG400, PEG600 for phase transfer synthesis of a-methyl cinnamaldehyde, the yield is 54.2%, the alpha-methyl cinnamaldehyde synthesized by this method has more negative reaction, product separation It is difficult to purify; 3, using benzaldehyde and n-propionaldehyde as raw materials, ethanol as solvent, TBAB as phase transfer catalyst, synthesizing a-methyl cinnamaldehyde under alkaline medium, the yield is 59.7%, the a-form synthesized by this method The synthesis process of cinnamaldehyde is simple, but the conversion rate of the raw material reaction is low, and the negative reaction is high, resulting in low product yield.

Company Contact:

• Posted By: Wuhan LANDMARK Industrial Co., Ltd.

• Phone: 02783916065

• Address: Jiang'an District of Wuhan, Wuhan , Hubei , China

• Email:

• Website: https://www.landmarkind.com

• Business Description: The company's main products are: cinnamic acid, cinnamaldehyde, cinnamon alcohol, methyl cinnamate, ethyl cinnamate, benzaldehyde and so on.
  
  The company has passed ISO9001 quality management system certification, and relying on the concept of independent development and joint development of universities, it has in-depth cooperation with major universities and scientific research institutions in Wuhan.
  
  It has successively obtained excellent companies with integrity standards, top ten outstanding private enterprises, and corporate credit evaluation AAA.
  
  Grade credit companies, etc.