Spop Antibody Biotin Conjugated - China

Product Name: SPOP Antibody, Biotin conjugated

Code : CSB-PA022601LD01HU

Uniprot NO.

: O43791

Storage : Upon receipt, store at -20°C or -80°C.

Avoid repeated freeze.

Immunogen : Recombinant human Speckle-type POZ protein (48-374AA)

Raised in : Rabbit

Species Reactivity : Human

Tested Applications : ELISA

Relevance : Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.

In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3 - In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation.

Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation.

The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.

Form : Liquid

Conjugate : Biotin

Storage Buffer : Preservative: 0.03% Proclin 300

Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Purification method : >95%, Protein G purified

Isotype : IgG

Clonality : Polyclonal

Alias : Speckle-type POZ protein, SPOP, HIB homolog 1, Roadkill homolog 1

Species : Human

Company Contact:

• Posted By: Wuhan Flarebio Biotech Inc.

• Phone: 862787196282

• Address: No.818, Gaoxin road.B11, Wuhan Hi-tech Medical Dev, Wuhan , China

• Email:

• Business Description: Flarebio is a high tech enterprise mainly engaged in the development,
  
  production and sales of vitro diagnostic reagents.
  
  It has provided high
  
  quality products includes gene, proteins, antibodies, Elisa kits,
  
  diagnostic reagent materials, drugs residue, food security
  
  micromolecule etc.