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  • Anti Active Rheb Mouse Monoclonal Antibody - USA

    price: contact company for price

    Catalog Number: 26910

    Gene Symbol: RHEB

    Description: Anti-Active Rheb Mouse Monoclonal Antibody

    Background: Small GTPases are a super-family of cellular signaling regulators.

    Rheb is a member of the Ras-superfamily GTPases.

    Rheb has been shown to interact with C-Raf, Mammalian target of rapamycin (mTOR), TSC2, Ataxia telangiectasia mutated (ATM), KIAA1303 and Ataxia telangiectasia and Rad3 related (ATR).

    Immunogen: Recombinant full length protein of active Rheb.

    Applications: IP, IHC

    Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP

    1: 100 dilution for IHC

    Concentration: 1 mg/ml

    Host: mouse

    Format: Liquid

    Clonality: Monoclonal

    Isotype: IgM

    Purity: Purified from ascites

    Storage buffer:

    Preservative: no

    Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

    Species Reactivity: Anti-active Rheb antibody recognizes active Rheb of vertebrates.

    Storage Conditions: Store at -20°C.

    Avoid freeze / thaw cycles


    Company Contact:


    • Phone: 6109452007

    • Address: 24 Whitewoods Lane, Malvern , PA , USA

    • Email: Email


    Published date: June 6, 2013

    • Business Description: NewEast Biosciences are specialized in generating protein configuration specific monoclonal antibodies that recognize active (GTP bound) G proteins (including Ras superfamily small GTPases and heterotrimeric G proteins).

      These unique antibodies do not recognize the inactive (GDP bound) G proteins.

      These monoclonal antibodies have been successfully used to immunoprecipitate active G proteins from cell lysates, and for immunohistochemical staining of active G proteins in cultured cells or in tissue sections.

      Hence, these antibodies can be used to study the spatial and temporal dynamics of cellular signaling involving big and small G proteins, the future direction of signal transduction studies.

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